Manufacturing Technology 2020, 20(6):779-784 | DOI: 10.21062/mft.2020.113

Zinc alloys as prospective materials for biodegradable medical devices

Jiří Kubásek1, Drahomír Dvorský1, Jaroslav Čapek2, Straková Markéta1, Hosová Klára1, Dalibor Vojtěch1
Jiří Kubásek1, Drahomír Dvorský1, Jaroslav Čapek2, Straková Markéta1, Hosová Klára1, Dalibor Vojtěch1
1 University of Chemistry and Technology Prague, Faculty of Chemical Technology, Department of Metals and Corrosion Engineering, Technická 5 166 28 Prague 6 – Dejvice, Czech Republic
2 FZU – The Institute of Physics, Czech Academy of Sciences, Na Slovance 1999/2, Prague 8, 182 21, The Czech Republic

Zinc-based materials are considered as promising materials for an application like biodegradable medical devices (bone fixations, stents). Such materials have to be characterized by an excellent combination of me-chanical, corrosion and biological properties. Presented paper is focused on the characterization of micro-structure and closely related mechanical properties for 3 zinc materials, namely pure Zn, Zn-0.8Mg and Zn-0.8Mg-0.2Sr. Studied alloys were prepared by gravity casting, homogenization treatment at 350 °C and extru-sion at 200 °C and extrusion ratio 11. Alloying by Mg caused the refinement of microstructure, formation of Mg2Zn11 phase and related improvement of mechanical properties like TYS and UTS for an extruded alloy. An additional encore of Sr causes a systematical improvement of TYS and UTS values, although the elonga-tion vas slightly decreased due to the presence of brittle SrZn13 phase.

Keywords: Zinc, magnesium, biodegradable materials, mechanical properties
Grants and funding:

Czech Science Foundation (project no. 18-06110S) and specific university research A1_FCHT_2020_003.

Received: August 28, 2020; Revised: November 27, 2020; Accepted: December 2, 2020; Prepublished online: December 11, 2020; Published: December 23, 2020  Show citation

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Kubásek J, Dvorský D, Čapek J, Markéta S, Klára H, Vojtěch D. Zinc alloys as prospective materials for biodegradable medical devices. Manufacturing Technology. 2020;20(6):779-784. doi: 10.21062/mft.2020.113.
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    References

    1. LI, G., YANG, H., ZHENG, Y., et al. (2019). Challenges in the use of zinc and its alloys as biodegradable metals: Perspective from biomechanical compatibility. In: Acta Biomater, Vol. 97, pp. 23-27. Elsevier Sci Ltd. England. ISSN: 17427061 Go to original source...
    2. LIU, Y., LU, B., CAI, Z. (2019). Recent Progress on Mg- And Zn-Based Alloys for Biodegradable Vascular Stent Applications. In: J Nanomater, Vol. 2019, pp. 1-16. Hindawi Ltd. England. ISSN: 16874110 Go to original source...
    3. SHUAI, C., LI, S., PENG, S., et al. (2019). Biodegradable metallic bone implants. In: Mater Chem Front, Vol. 3, No. 4, pp. 544-62. Royal Society of Chemistry. England. ISSN: 20521537 Go to original source...
    4. VENEZUELA, J., DARGUSCH, MS. (2019). The influence of alloying and fabrication techniques on the mechanical properties, biodegradability and biocompatibility of zinc: A comprehensive review. In: Acta Biomater, Vol. 87, pp. 1-40. Pergamon-Elsevier Science Ltd. England. ISSN: 17427061 Go to original source...
    5. SHI, ZZ., GAO, XX., ZHANG, HJ., et al. (2020). Design biodegradable Zn alloys: Second phases and their significant influences on alloy properties. In: Bioact Mater, Vol. 5, No. 2, pp. 210-8. Keai Publishing Ltd. PEOPLES R CHINA. ISSN: 2452199X Go to original source...
    6. KUBASEK, J., VOJTECH, D., JABLONSKA, E., et al. (2016). Structure, mechanical characteristics and in vitro degradation, cytotoxicity, genotoxicity and mutagenicity of novel biodegradable Zn-Mg alloys. In: Mater Sci Eng C-Materials Biol Appl, Vol. 58, pp. 24-35. Elsevier Ltd. England. ISSN: 09284931 Go to original source...
    7. KUBASEK, J., VOJTECH, D., POSPISILOVA, I., et al. (2016), Microstructure and mechanical properties of the micrograined hypoeutectic Zn-Mg alloy. In: Int J Miner Metall Mate, Vol. 23, No. 10, pp. 1167-76. Springer. USA. ISSN: 16744799 Go to original source...
    8. KUBASEK, J., POSPISILOVA, I., VOJTECH, D. et al. (2014). Structural, mechanical nad cytotoxicity characterization of as-cast biodegradable Zn-xMg (x=0.8-8.3 %) alloys. In: Mater Tehnol., Vol. 48, No. 5, pp. 623-9. Inst za kovinske materiale in technologie. Slovenia. ISSN: 15802949
    9. POSPISILOVA, I., VOJTECH, D., KUBASEK, J. (2014). Structure and properties of zn-mg alloys for medical implants. In: Manuf Technol, Vol. 14, No. 3, pp. 422-7. Univerzita J. E. Purkyne. Czech Republic. ISSN: 12132489 Go to original source...
    10. LIU, XW., SUN, JK., QIU, KJ., et al. (2016). Effects of alloying elements (Ca and Sr) on microstructure, mechanical property and in vitro corrosion behavior of biodegradable Zn-1.5Mg alloy. In: J Alloys Compd., Vol. 664, pp. 444-52. Elsevier Science SA. Switzerland. ISSN: 09258388 Go to original source...
    11. OKAMOTO H. (2010) Desk Handbook: Phase Diagrams for Binary Alloys, ASM International, ASM Handbooks Series.
    12. CAPEK, J., KUBASEK, J., PINC, J., et al. (2020). ZnMg0.8Ca0.2 (wt%) biodegradable alloy - The influence of thermal treatment and extrusion on microstructural and mechanical characteristics. In: Mater Charact., Vol. 162, No. 17. Elsevier Science INC. USA. ISSN: 10445803 Go to original source...
    13. CAPEK, J., KUBASEK, J., PINC, J., et al. (2020). Extrusion of the biodegradable ZnMg0.8Ca0.2 alloy - The influence of extrusion parameters on microstructure and mechanical characteristics. In: J Mech Behav Biomed Mater., Vol. 108, No. 16. Elsevier Ltd. England. ISSN: 17516161 Go to original source...
    14. VOJTECH, D., KUBASEK, J., SERAK, J., et al. (2011). Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation. In: Acta Biomater., Vol. 7, No. 9, pp. 3515-22. Elsevier Sci Ltd. England. ISSN: 17427061 Go to original source...
    15. DVORSKY, D., KUBASEK, J., VOJTECH, D., et. al. (2016). Structure and mechanical properties of WE43 prepared by powder metallurgy route. In: Manuf Technol, Vol. 16, No. 5, pp. 896-902. Univerzita J. E. Purkyne. Czech Republic. ISSN: 12132489 Go to original source...
    16. DVORSKY, D., KUBASEK, J., VOJTECH, D., et. al. (2016). Preparation of WE43 using powder metallur-gy route. In: Manuf Technol, Vol. 16, No. 4, pp. 680-687. Univerzita J. E. Purkyne. Czech Republic. ISSN: 12132489 Go to original source...

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